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pentobarbital will reduce the level or outcome of voriconazole by affecting hepatic enzyme CYP2C9/10 metabolism. Slight/Significance Not known.pentobarbital will reduce the level or result of bexarotene by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.pentobarbital will minimize the level or impact of lumacaftor/ivaca